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96T Human TRAP 5 ELISA Kit

北京科瑞美科技有限公司

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價(jià)格：電議

所在地：北京

型號(hào)：96T

更新時(shí)間：2024-04-22

瀏覽次數(shù)：1563

公司地址：北京市海淀區(qū)廂黃旗2號(hào)樓1層4-179室

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產(chǎn)品簡(jiǎn)介

產(chǎn)品名稱：Human TRAP 5? ELISA Kit 貨號(hào)：RD0 規(guī)格：96T 產(chǎn)地：捷克

公司簡(jiǎn)介

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產(chǎn)品說(shuō)明

產(chǎn)品名稱：Human TRAP 5 ELISA Kit
貨號(hào)：RD197025000
規(guī)格：96T
產(chǎn)地：捷克

1. INTENDED USE
The RD197025000 Human TRAP 5 Assay is an ImmunoCapture Enzyme-Activity Assay for the quantitative measurement of human TRAP 5 in serum and EDTA plasma.

2.Features
· European unio: for in vitro diagnostic use
Rest of the world: for research use only!
· The total assay time is less than 4 hours
· The kit measures TRAP 5 proteins exhibiting enzyme activity in serum and EDTA plasma
· Assay format is 96 wells
· Quality Controls are recombinant TRAP 5 protein based. No animal sera are used
· Calibrators are recombinant protein based
· Components of the kit are provided ready to use, concentrated or lyophilized

3. INTRODUCTION
TRAP 5 (serum band 5 tartrate-resistant acid phosphatase, TRACP 5; EC 3.1.3.2) is a
glycoprotein of 35-37 kDa. TRAP 5 belongs to the most abundant enzymes in osteoclasts. It is expressed in certain differentiated cells of the mononuclear phagocyte system, particularly osteoclasts and alveolar macrophages, where it takes an active part in bone resorption process.

High blood levels of TRAP 5 are usually associated with active bone remodelling. Increased
serum levels are observed during normal bone growth among healthy children.
Elevated serum TRAP levels have been detected in diseases characterized by increased bone resorption; Paget’s disease of the bone, hemodialysis, primary hyperparathyroidism, metastatic malignancies involving bone resorption, multiple myeloma and bilaterally ovariectomized women. Post-menopausal women have higher levels of serum than post-menopausal women on estrogen replacement therapy.

Therefore specific determination of TRAP 5 activity can be essential for clinical assessment of bone metabolism.

Cross-Reactivity

human	Yes
bovine	Non-detectable
cat	Non-detectable
chicken	Not tested
dog	Yes
goat	Non-detectable
hamster	Non-detectable
horse	Non-detectable
monkey	Yes
mouse	Non-detectable
pig	Non-detectable
rabbit	Yes
rat	Non-detectable
sheep	Non-detectable

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